The adrenal glands may be lacking in the body, or be present excessively. Both cases are a risk.
The thyroid is susceptible to various diseases such as nodules, malfunction and even cancer gland. Treatment of these diseases depends on the same. For any abnormality or problem with the thyroid consult an endocrinologist.
Metabolism in general can be divided conceptually into many parts but is usually done in 2 mainly is anabolism and catabolism. When there is an abnormal metabolism it is when you consider that there is a disease.
Osteoporosis is a common disease occurring in decreased bone mineral density. Some diseases can accelerate bone loss such as thyroid deficiency and male and female hormones (premature menopause), among others.