IL
Dr. Iván Linares Cervantes PhDCirugía General, Hígado y Trasplantes en Cuernavaca
IL
Dr. Iván Linares Cervantes PhD
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Por qué es un especialista de primer nivel
El Dr. Iván Linares Cervantes se graduó como Médico Cirujano de la Universidad Autónoma de San Luis Potosí (UASLP). Posteriormente, cursó la Especialidad en Cirugía General en la Universidad Nacional Autónoma de México (UNAM), la Subespecialidad en Cirugía Hepática, Vías Biliares y Trasplantes Abdominales (Hígado, Riñón y Páncreas) en la Universidad de Cincinnati y el Doctorado en Máquina de Perfusión Ex Vivo Normotérmica como Técnica de Preservación de Órganos en la Universidad de Toronto.
Es experto en:
- Trasplante Hepático
- Cirrosis
- Cáncer de Hígado
- Cirugía Biliar
- Cirugía General
- Trasplante Renal
- Trasplante de Páncreas
- Cirugía de Vesícula y Vías Biliares
- Enfermedades del Hígado
- Cirugía de Donador Vivo
Es Médico Adscrito al Departamento de Cirugía de Trasplantes del Hospital Regional Número 1 IMSS Cuernavaca y pertenece al Sistema Nacional de Investigadores (SNI) con Nivel I de distinción.
Es miembro de diversas organizaciones médicas, tales como:
- International Liver Transplantation Society
- American Society of Transplant Surgeons
- Canadian Society of Transplantation
- Colegio Mexicano de Cirugía
- Canadian Donation and Transplantation Research Program
Actualmente el especialista atiende a sus pacientes en el Hospital San Diego Cuernavaca.
Consultas
Consultorio Médico Privado
Cuernavaca, Plan de Ayutla No. 13, Col. Reforma, 62260Seguros médicos aceptados
Este especialista no tiene activada esta información
Consultorio Médico Privado
Currículum
Experiencia profesional
- 12 años de experiencia
- Médico Especialista. Hospital San Diego en el Hospital Cuernavaca. Actualidad
- Médico Adscrito. Departamento de Cirugía Hepato Pancreato Biliar y Trasplantes Abdominales. Hospital Ángeles Acoxpa. Ciudad de México. 2023
- Cirujano General. Star Médica HIP. Ciudad de México. 2023
- Médico Adscrito. Departamento de Cirugía Hepato Pancreato Biliar y Trasplantes Abdominales. Centro Médico Naval (CEMENAV). Ciudad de México. 2023
- Médico Adscrito. Departamento de Cirugía General. Hospital Civil de Ciudad Victoria. 2015
Subespecialización
- Revisor. Frontiers in Medicine. 2021 - Actualidad
- Revisor. Transplantation Direct. 2021 - Actualidad
- Revisor. Transplantation Journal. 2020 - Actualidad
- Revisor. Surgery Journal. 2020 - Actualidad
- Revisor. American Journal of Transplantation. 2020 - Actualidad
- Revisor. Journal of Tissue Engineering. 2019 - Actualidad
- Revisor. Journal of Medical Systems. 2017 - Actualidad
- Investigador. Distinción Nivel I. Sistema Nacional de Investigadores (SNI). Consejo Nacional de Ciencia y Tecnología (Conacyt)
Miembro de asociaciones médicas privadas
- International Liver Transplantation Society
- American Society of Transplant Surgeons
- Canadian Society of Transplantation
- Colegio Mexicano de Cirugía
- Canadian Donation and Transplantation Research Program
Logros académicos destacados
- Fellowship. Departamento de Trasplantes Abdominales (Hígado, Riñón, Páncreas, Accesos Vasculares). Universidad de Cincinnati. Estados Unidos. 2021
- Philosophie Doctor (PhD). Ciencias Médicas. Universidad de Toronto. Canadá. 2019
- Fellow de Investigación. Toronto Organ Preservation Laboratory, Department of Multi Organ Transplant, University Health Network MaRS. Toronto. 2018
- Especialidad. Cirugía General. Universidad Nacional Autónoma de México (UNAM). Ciudad de México. 2015
- Licenciatura. Médico Cirujano. Universidad Autónoma de San Luis Potosí (UASLP). San Luis Potosí. 2010
Docencia
- Profesor de Cirugía. Residencia de Cirugía General, Departamento de Cirugía. Hospital Regional Número 1 IMSS Cuernavaca
- Instructor Quirúrgico. Residencia de Cirugía General. Departamento de Cirugía. Universidad de Cincinnati. 2019 - 2021
- Instructor. Embriología. Universidad Autónoma de San Luis Potosí (UASLP). 2004
- Instructor. Histología. Universidad Autónoma de San Luis Potosí (UASLP). 2004
Cargos en Organizaciones
- Revisor. Frontiers in Medicine. 2021 - Actualidad
- Revisor. Transplantation Direct. 2021 - Actualidad
- Revisor. Transplantation Journal. 2020 - Actualidad
- Revisor. Surgery Journal. 2020 - Actualidad
- Revisor. American Journal of Transplantation. 2020 - Actualidad
- Revisor. Journal of Tissue Engineering. 2019 - Actualidad
- Revisor. Journal of Medical Systems. 2017 - Actualidad
- Investigador. Distinción Nivel I. Sistema Nacional de Investigadores (SNI). Consejo Nacional de Ciencia y Tecnología (Conacyt)
Publicaciones y conferencias
- Orador. Trasplante Hepático de Donador en Parada Circulatoria. 9º Congreso de la Asociación Mexicana de HPB. Ciudad de México. 2021
- Orador. Máquina de Perfusión como Técnica de Preservación Ex-situ. 9º Congreso Estatal de Puebla. Unidad de Trasplantes de Puebla. Puebla. 2021
- Asistencia. Actualización ACLS y BLS. University of Cincinnati. 2021
- Publicación. Urbanellis P, Mazilescu L, Kollmann D, Linares-Cervantes I, Kaths JM, Ganesh S, Oquendo F, Sharma M, Goto T, Noguchi Y, John R, Konvalinka A, Mucsi I, Ganhekar A, Bagli D, Robinson LA, Selzner M. Prolonged Warm Ischemia Time Leads to Severe Renal Dysfunction of Donation-after-cardiac Death Kidney Grafts. Scientific Reports-Nature. September 2021. 17930. 2021
- Publicación. Urbanellis P, McEvoy CM, Škrtić M, Kaths JM, Kollmann D, Linares I, Ganesh S, Oguendo F, Sharma M, Mazilescu L, Goto T, Noguchi Y, John R, Mucsi I, Ghanekar A, Bagli D, Konvalinka A, Selzner M, Robinson L. Transcriptome Analysis of Kidney Grafts Subjected to Normothermic Ex-Vivo Perfusion Demonstrates an Enrichment of Mitochondrial Metabolism Genes. Transplantation direct. August 2021. Volume 7 - Issue 8 - p e719 doi: 10.1097/TXD.0000000000001157. 2021
- Publicación. Mamatha B, Linares-Cervantes I, Pasini E, Patel P, Goto T, Noguchi Y, Mazilescu L, Urbanellis P, Selzner M, Selzner N. Normothermic Ex Situ Liver Perfusion Enhances Mitochondrial Function of DCD Grafts as Evidenced by High-Throughput Metabolomics. Transplantation. July, 2021- Volume 105 Issue 7. P 1530-1538 Doi: 10.1097/TP.0000000000003476. 2021
- Publicación. Jaramillo-Gante MA, Acosta-Hernández CE, Castro-Casillas PR, Linares-Cervantes IJ. Allotransplantation of Ligated Arteriovenous Fistula as a Novel Strategy for Patients with Multiple Vascular Access Failures (D-226). American Journal of Transplantation. 2020 Apr; 20 Suppl 3:5-1166. Doi: 10.1111/ajt.16169. Page 218. 2020
- Orador. Presentación de Caso Carcinoma Hepatocelular #1. 8th Asociación Mexicana de HPB. Congreso 2020. Ciudad de México. 2020
- Publicación. Libro: Pruebas de Laboratorio e Imagen en Gastroenterología y Hepatología (3a Edición); Capítulo, Gravedad de la Enfermedad Hepática. Dr. Nahum Méndez. 2020
- Publicación. Urbanellis P, Kollmann D, Linares I, Ganesh S, Oquendo F, Mazilescu L, Goto T, Noguchi Y, John R, Konvalinka A, Mucsi I, Ghanekar A, Bagli D, Selzner M, Robinson L. Significant Dysfunction of Kidney Grafts Exposed to Prolonged Warm Ischemia is Minimized Through Normothermic Ex Vivo Kidney Perfusion. Transplantation Direct. August 2020-Volume 6, Issue 8-p e587. 2020
- Publicación. Kollmann D, Linares I, Ganesh S, Rosales R, Hamar M, Goto T, Urbanellis P, Tessandier N, Boilard E, Bruguera C, Wiebe A, Bartczak A, Yip P, Adeyi O, Selzner M, Selzner N. Normothermic Ex Vivo Liver Perfusion Prevents Intrahepatic Platelet Sequestration After Liver Transplantation. Transplantation. June 2020-Volume 104, Issue 6, p. 1177 - 1186. 2020
- Publicación. Diwan T, Cuffy M, Linares-Cervantes I, Govil A. Impact of Obesity on Dialysis and Transplant and its Management. Seminars in Dialysis. 2020 May; 33 (3) : 279-285 doi: 10.1111/sdi.12876. Epub 2020 April 10. 2020
- Publicación. Urbanellis P, Hamar M, Kaths JM, Kollmann D, Linares I, Ganesh S, Wiebe A, Yip PM, John R, Konvalinka A, Mucsi I, Ganhekar A, Bagli DJ, Robinson LA, Selzner M. Normothermic Ex-vivo Kidney Perfusion Improves Early DCD Graft Function Compared to Hypothermic Machine Perfusion and Static Cold Storage. Transplantation. 2020 May; 104 (5): 947-955 doi: 10.1097/TP.0000000000003066. 2020
- Publicación. Jaramillo-Gante MA, Acosta-Hernández CE, Castro-Casillas PR, Linares-Cervantes IJ. Allotransplantation of Ligated Arteriovenous Fistula as a Novel Strategy for Patients with Multiple Vascular Access Failures (D-226). American Journal of Transplantation. 2020 Apr; 20 Suppl 3:5-1166. Doi: 10.1111/ajt.16169. Page 218. 2020
- Publicación. Urbanellis P, McEvoy C, Skrtic M, Linares I, Kollmann D, Oquendo F, Ganesh S, Mazilescu L, Sharma M, Bagli D, Mucsi I, Ghanekar A, Konvalinka A, Robinson L, Selzner M. Mitochondrial Metabolism is Preserved Following Normothermic Ex-Vivo Kidney Perfusion of Grafts Procured Following Cardiac Death. Transplantation. September 2020- Volume 104-Issue S3- p S249. doi: 10.1097/01.tp.0000699720.63874.6a. 2020
- Publicación. Urbanellis P, Mazilescu L, McEvoy C, Linares I, Kollmann D, Goto T, Noguchi Y, Ganesh S, John R, Mucsi I, Ghanekar A, Bagli D, Konvalinka A, Robinson L, Selzner M. GenomeWide Transcriptome Analysis of Extreme Marginal Renal Grafts Indicates Earlier Repair and Less Damage Following Normothermic Ex-Vivo Kidney Perfusion Preservation. Transplantation. September 2020-Volume 104- Issue S3- p S250. doi: 10.1097/01.tp.0000699732.56864.3e. 2020
- Publicación. Urbanellis P, Linares I, Kollmann D, Ganesh S, Mazilescu L, Oquendo F, Wiebe A, John R, Mucsi I, Ghanekar A, Bagli D, Konvalinka A, Robinson L, Selzner M. Normothermic Ex-Vivo Kidney Perfusion Preservation Reliably Improves Marginal Graft Function Compared to Hypothermic Machine Perfusion. Transplantation. September 2020-Volume 104- Issue S3- p S251. doi: 10.1097/01.tp.0000699736.35529.4c. 2020
- Publicación. Mazilescu L, Kaths M, Urbanellis P, Hamar M, Goto T, Linares-Cervantes I, Noguchi Y, Konvalinka A, Ghanekar A, Bagil D, John R, Robinson L, Selzner M. Normothermic ExVivo Kidney Perfusion is Superior to Anoxic and Oxygenated Hypothermic Machine Perfusion for the Preservation of DCD Porcine Kidney Grafts (525). American Journal of Transplantation. 2020 Apr; 20 Suppl 3:5-1166. Doi: 10.1111/ajt.16169. Page 41. 2020
- Publicación. Urbanellis P, McEvoy C, Kaths M, Hamar M, Mazilescu L, Linares I, Kollmann D, Goto T, Noguchi Y, Ganesh S, John R, Mucsi I, Ghanekar A, Bagli D, Konvalinka A, Robinson L, Selzner M. Mitochondrial Metabolism is Enriched Following Normothermic Ex-Vivo Kidney Perfusion of Grafts Procured Following Cardiac Death (P-119). American 14 Journal of Transplantation. 2020 Jan; 20 Suppl 2:13-98. Doi: 10.1111/ajt.15715. Page 65. 2020
- Publicación. Urbanellis P, Mazilescu L, Hamar M, McEvoy C, Linares I, Kollmann D, Goto T, Noguchi Y, Ganesh S, John R, Mucsi I, Ghanekar A, Bagli D, Konvalinka A, Robinson L, Selzner M. Genome-wide Transcriptome Analysis of Extreme Marginal Renal Grafts Indicates Earlier Repair and Less Damage Following Normothermic Ex-Vivo Kidney Perfusion Preservation. American Journal of Transplantation. 2020 Jan; 20 Suppl 2:13-98. Doi: 10.1111/ajt.15715. Page 65. 2020
- Autor. Póster: Allotransplantation of Ligated Arteriovenous Fistula as a Novel Strategy for Patients with Multiple Vascular Access Failures (D-226). American Transplant Congress. 2020
- Organizador. Internacional Liver Transplantation Society. Taller de Perfusión de Órganos. Ontario. 2019
- Orador. Máquina de Perfusión para Preservación de Hígado y Riñón. Grand Rounds. Nueva York. 2019
- Publicación. Linares-Cervantes I, Selzner M. Letter to the Editor-Reply. Splenectomy as Flow Modulation Strategy and Risk Factors of De-novo Portal Vein Thrombosis in Adult-to Adult Living Donor Liver Transplant. Liver Transpl. 2019 Aug; 25 (8):1284. doi: 10.1002/lt.25576. Epub 2019 May 29. 2019
- Publicación. Linares-Cervantes I, Echeverri J, Cleland S, Kaths M, Rosales R, Goto T, Kollmann D, Hamar M, Urbanellis P, Mazilescu L, Ganesh S, Adeyi O, Yip P, Gorynzka P, Gorynzki K, David R. Grant, Nazia Selzner, Marcin Wasowicz, Markus Selzner. Predictor Parameters of Liver Viability During Porcine Ex-Vivo Liver Perfusion in a Model of Liver Transplantation with Marginal Grafts. American Journal of Transplantation. 2019;19:2991-3005. April 23. 2019
- Publicación. Linares I, Kollmann D, Echeverri J, Kaths M, Ganesh S, Hamar M, Urbanellis P, Rosales R, Bruguera C, Yip P, Adeyi O, Selzner M, Selzner N. Impact of Different Clinical Perfusates during Normothermic Ex Vivo liver Perfusion on Pig Liver Transplantation Outcomes in a DCD Model. Transplantation Direct. April 2019-Volume 5-Issue 4-p e437. doi: 10.1097/TXD.0000000000000876. 2019
- Publicación. Linares I, Hamar M, Selzner N, Selzner M. Steatosis in liver transplantation: Current limitations and future strategies. Transplantation. 2019 Jan; 103(1):78-90. doi: 10.1097/TP.0000000000002466. 2019
- Publicación. Linares-Cervantes I, Kollmann D, Goto T, Echeverri J, Kaths M, Hamar M, Urbanellis P, Mazilescu L, Rosales R, Bruguera C, Oquendo F, Ganesh S, Adeyi O, Yip P, Selzner M, Selzner N. Assessment of Clinical Perfusates for Normothermic Ex-situ Liver Perfusion in a Pig Transplant Model with DCD Grafts. Transplantation. 103(8S): 1-491. O-081. 2019
- Autor. Póster: In-vitro and In-vivo PPAR-y Administration Reduces M1-Nitric Oxide+ Macrophages and Improves Hepatic Ischemia Reperfusion Injury. 2019 ASTS Winter Symposium. Miami. 2019
- Publicación. Linares-Cervantes I, Echeverri J, Cleland S, Kaths M, Rosales R, Goto T, Kollmann D, Hamar M, Urbanellis P, Mazilescu L, Ganesh S, Adeyi O, Yip P, Bojko B, Gorynzka P, Gorynzki K,David R. Grant, Nazia Selzner, Marcin Wasowicz, Markus Selzner. Liver Viability Parameters During Normothermic Ex-situ Liver Perfusion in a Porcine Model of Liver Transplantation with Marginal Grafts. Transplantation. 103(8S): 1-491. O-151. 2019
- Publicación. Linares-Cervantes I, Kollmann D, Goto T, Echeverri J, Kaths M, Ganesh S, Hamar M, Urbanellis P, Rosales R, Bruguera C, Oquendo F, Yip P, Adeyi O, Selzner M, Selzner N. Normothermic Ex Situ Liver Perfusion with Different Clinical Perfusates and Their Effect on Pig Liver Transplant Outcomes in a Donation after Circulatory Death Model. American Journal of Transplantation. 2019 Apr; 19 Suppl 3:5-1167. Doi: 10.1111/ajt.15404. Page 162. 2019
- Publicación. Linares-Cervantes I, Echeverri J, Cleland S, Kaths M, Rosales R, Goto T, Kollmann D, Hamar M, Urbanellis P, Mazilescu L, Ganesh S, Adeyi O, Yip P, Bojko B, Gorynzka P, Gorynzki K,David R. Grant, Nazia Selzner, Marcin Wasowicz, Markus Selzner. Normothermic Ex-Situ Liver Perfusion Parameters of Liver Viability in a Porcine Model of Liver Transplantation with Marginal Grafts. American Journal of Transplantation. 2019 Apr;19 Suppl 3:5-1167. Doi: 10.1111/ajt.15404. Page 199. 2019
- Publicación. Linares-Cervantes I, Echeverri J, Cleland S, Kaths M, Rosales R, Goto T, Kollmann D, Hamar M, Urbanellis P, Mazilescu L, Ganesh S, Adeyi O, Yip P, Gorynzka P, Gorynzki K, David R. Grant, Nazia Selzner, Marcin Wasowicz, Markus Selzner. Predictor Variables of Hepatic Viability During Normothermic Ex-Situ Perfusion in a Porcine Model of Liver Transplantation with Extremely Ischemic Grafts. American Journal of Transplantation. 2019 Jan; 19 Suppl 1:13-97. Doi: 10.1111/ajt.15186. Page 34. 2019
- Autor. Póster: Predictor Variables of Hepatic Viability During Normothermic Ex-situ Perfusion in a Porcine Model of Liver Transplantation with Extremely Ischemic Grafts. 2019 ASTS Winter Symposium. Miami. 2019
- Publicación. Linares-Cervantes I, Bartczak A, Kaveh F, Kaths M, Echeverri J, Ganesh S, Kollmann D, Hamar M, Urbanellis P, Yip P, Adeyi O, Selzner M, Selzner N. In Vitro and In Vivo PPARy Administration Reduces M1-Nitric Oxide+ Macrophage and Improves Hepatic Ischemia Reperfusion Injury. American Journal of Transplantation. 2019 Jan; 19 Suppl 1:13-97. Doi: 10.1111/ajt.15186. Page 34. 2019
- Publicación. Bhat M, Linares I, Passini E, Goto T, Selzner M, Selzner N. Normothermic Ex Situ Liver Perfusion of Donation after Cardiac Death Grafts Improves Mitochondrial Function. Transplantation. 103(8S): 1-491. P-282. 2019
- Publicación. Goto T, Linares I, Ganesh S, Ruban J, Mazilescu L, Urbanellis P, Uemoto S, Selzner M, Selzner N. New Assessment Method: Indocyanine Green Fluorescence Imaging During Normothermic Ex Vivo Liver Perfusion for DCD Graft. Transplantation. 103(8S): 1-491. P-005. 2019
- Autor. Póster: Normothermic Ex Situ Liver Perfusion with Different Clinical Perfusates and Their Effect on Pig Liver Transplant Outcomes in a Donation after Circulatory Death Model. 2019 ATC Congress. Boston. 2019
- Autor. Póster: Normothermic Ex-Situ Liver Perfusion Parameters of Liver Viability in a Porcine Model of Liver Transplantation with Marginal Grafts. 2019 ATC Congress. Boston. 2019
- Publicación. Urbanellis P, Hamar M, Linares I, Kollmann, Ganesh S, Oquendo F, Sharma M, John R, Ghanekar A, Mucsi I, Bagli D, Konvalinka A, Robinson L, Selzner M. Normothermic ExVivo Kidney Perfusion Preservation Consistently Improves Extreme Marginal Graft Function Compared to Hypothermic Machine Perfusion (Abstract #600). American Journal of Transplantation. 2019 Apr; 19 Suppl 3:5-1167. Doi: 10.1111/ajt.15404. Page 139
- Orador. Assessment of Clinical Perfusates for Normothermic Ex-situ Liver Perfusion in a Pig Transplant Model with DCD Grafts. 2019 ILTS Annual International Congress. Toronto. 2019
- Publicación. Goto T, Linares I, Ganesh S, Mazilescu L, Urbanellis P, Selzner M. Indocyanine Green Fluorescence Imaging during Normothermic Ex Vivo Liver Perfusion for the Assessment of Hepatocyte, Biliary, and Vascular Function. American Journal of Transplantation. 2019 Apr; 19 Suppl 3:5-1167. Doi: 10.1111/ajt.15404. Page 159. 2019
- Publicación. Urbanellis P, Hamar M, Kaths M, McEvoy C, Linares I, Ganesh S, John R, Mucsi I, Ghanekar A, Bagli D, Grant D, Konvalinka A, Robinson L, Selzner M. Normothermic ExVivo Kidney Perfusion Restores the Gene Expression Profile of Marginal Kidney Grafts Subjected to Warm Ischemia. American Journal of Transplantation. 2019 Jan: 19 Suppl 1:13-97 Doi: 10.1111/ajt.15186. Page 17. 2019
- Publicación. Urbanellis P, Hamar M, Kollmann D, Linares I, Ganesh S, John R, Konvalinka A, Mucsi I, Ghanekar A, Bagli D, Grant D, Robinson L, Selzner M. Normothermic Ex-Vivo Kidney Perfusion Preservation Reliably Improves Marginal Graft Function Compared to Hypothermic Machine Perfusion. American Journal of Transplantation. 2019 Jan: 19 Suppl 1:13-97 Doi: 10.1111/ajt.15186. Page 85. 2019
- Orador. Liver Viability Parameters During Normothermic Ex-situ Liver Perfusion in a Porcine Model of Liver Transplantation with Marginal Grafts. 2019 ILTS Annual International Congress. Toronto. 2019
- Proyecto. Modelo Experimental de Perfusión Normotérmica y Estrategias para Mejorar los Resultados Posterior a Trasplante. Actividad: 180 Trasplantes Hepáticos y 40 Trasplantes Renales en Modelo Porcino. Fellow de Investigación en el Laboratorio de Preservación de Órganos de Toronto. 2018
- Proyecto. Estudio clínico (humanos) de Máquina de perfusion ex situ normotérmica hepática (29 perfusiones hepáticas). Fellow de investigación en el Laboratorio de Preservación de Organos de Toronto. 2018
- Proyecto: Modelo de Isquemia/Reperfusión Hepática en Modelo de roedores. Fellow de Investigación en el Laboratorio de Preservación de Órganos de Toronto. 2018
- Proyecto. Análisis de Base de Datos para Resultados y Complicaciones Posterior a Trasplante Hepático. Fellow de Investigación en el Laboratorio de Preservación de Órganos de Toronto. 2018
- Orador. Perfusión Normotérmica (Trasplante Hepático). Congreso de la Sociedad Mexicana de Trasplante. Querétaro. 2018
- Publicación. Linares I, Selzner N, Selzner M. Perfusion Strategies and Organ Repair: Where is the Limit? November 9, 2018 (Syllabus) Page 32-52. 2018 AASLD/ILTS Transplantation Course: Expanding the Boundaries for Liver Transplant Oncology. 2018
- Sonya A. MacParland, Jeff C.Lui , Xue-Zhong, Brendan Innes, Agata Bartczak, Blair K. Gage, Justin Manuel, Nicholas Khuu, Juan Echeverri, Iván Linares, Rahul Gupta, Michael Cheng et al. Single Cell RNA Sequencing of Human Liver Reveals Distinct Intrahepatic Macrophage Populations. Nature Communications. 2018 October;9 (1):4383. doi: 10.1038/s41467-018-06318-7. 2018
- Publicación. Linares I, Goldaracena N, Rosales R, De la Maza L, Kollmann D, Kaths M, Echeverri J, McCluskey S, Selzner N, Sapisochin G, Lilly L, Greig P, Bhat M, Ghanekar A, Cattral M, McGilvray I, Grant D, Selzner M. Splenectomy as Flow Modulation Strategy and Risk Factors of De-novo Portal Vein Thrombosis in Adult-to-Adult Living Donor Liver Transplant. Liver Transpl. 2018 Sep; 24(9): 1209-1220. doi: 10.1002/lt.25212. 2018
- Publicación. Kollmann D, Goldaracena N, Linares I, Selzner N, Sapisochin G, Lilly L, Greig P, Bhat M, Ghanekar A, Cattral M, McGilvray I, Grant D, Selzner M. Live Donor Liver Transplantation Using Selected Grafts with Two Bile Ducts Compared to One Bile Duct Does not Impact on Patient Outcome. Liver Transplantation Journal. 2018 Nov; 24 (11): 1512-1522. Doi: 10.1002/lt.25197. 2018
- Publicación. Hamar M, Urbanellis P, Kaths JM, Kollmann D, Linares I, Ganesh S, Wiebe A, Cen JY, Yip PM, John R, Konvalinka A, Mucsi I, Ghanekar A, Bagli DJ, Grant DR, Robinson LA, Selzner M. Normothermic Ex Vivo Kidney Perfusion Reduces Warm Ischemic Injury of Porcine Kidney Grafts Retrieved After Circulatory Death (DCD). Transplantation Journal 2018 Aug;102(8):1262-1270. doi: 10.1097/TP.0000000000002245. 2018
- Publicación. Linares I, Selzner N, Selzner Markus. Machine Preservation of the Liver: What is the Future Holding? Current Transplantation Reports (2018) 5: 82-92. 2018
- Publicación. Juan Echeverri, Nicolas Goldaracena, Johan Moritz Kaths, Iván Linares, Roizar Roizales, Dagmar Kollmann, Matyas Hamar, Peter Urbanellis, Sujani Ganesh, Oyedele A. Adeyi, Markus Selzner, Nazia Selzner (2018). Comparison of BQ123, Epoprostenol, and Verapamil as Vasodilators During Normothermic Ex Vivo Liver Machine Perfusion. Transplantation. 2018 Apr; 102(4): 601-608. doi: 10.1097/TP.0000000000002021. 2018
- Publicación. J. Moritz Kaths, Mátyás Hamar, Juan Echeverri, Iván Linares, Peter Urbanellis, Jun Yu Cen, Sujani Ganesh, Luke S. Dingwell, Paul Yip, Rohan John, Darius Bagli, Istvan Mucsi, Anand Ghanekar, David Grant, Lisa A. Robinson, Markus Selzner. (2017). Normothermic Ex Vivo Kidney Perfusion for Graft Quality Assessment Prior to Transplantation. American Journal of Transplantation. 2018 Mar;18(3):580-589. Doi: 10.1111/ajt.14491. 2018
- Publicación. Linares I, Bartczak A, Kaveh F, Kaths M, Echeverri J, Ganesh S, Kollmann D, Hamar M, Urbanellis P, Yip P, Adeyi O, Selzner M, Selzner N. In Vitro and In Vivo Administration of PPAR-y Agonist Reduces M1-Nitric Oxide+ Macrophage Phenotype and Ameliorates Hepatic Ischemia Reperfusion Injury. Hepatology. 2018 October 1; 68 (S1). Page 123A. https://doi.org/10.1002/hep.30256. 2018
- Publicación. Linares I, Bartczak A, Kaveh F, Kaths M, Echeverri J, Ganesh S, Kollmann D, Hamar M, Urbanellis P, Yip P, Adeyi O, Selzner M, Selzner N. In Vivo and In Vitro PPAR-y Activation Decreases M1-Macrophage Polarization and Improves Liver Ischemia Reperfusion Injury. American Journal of Transplantation. 2018 May 4;18 Suppl 4:p129. doi: 10.1111/ajt.14916. 2018
- Publicación. Linares I, Bartczak A, Kaveh F, Kaths M, Echeverri J, Ganesh S, Kollmann D, Hamar M, Urbanellis P, Yip P, Adeyi O, Selzner M, Selzner N. In Vivo and In Vitro PPAR-y Activation Decreases M1-Macrophage Polarization and Improves Liver Ischemia Reperfusion Injury. Transplantation Journal. May 2018- Volume 102- Issue 5S. O-035 doi: 10.1097/01.tp.0000534078.18014.88. 2018
- Publicación. Linares I, Bartczak A, Kaveh F, Kaths M, Echeverri J, Ganesh S, Kollmann D, Hamar M, Urbanellis P, Yip P, Adeyi O, Selzner M, Selzner N. In Vivo and In Vitro PPAR-y Activation Decreases M1-Macrophage Polarization and Improves Liver Ischemia Reperfusion Injury. Transplantation Journal. July 2018 - Volume 102 - Issue - p S708. doi: 10.1097/01.tp.0000543674.85457.9b. 2018
- Publicación. Linares I, Kollmann D, Echeverri J, Kaths M, Ganesh S, Hamar M, Urbanellis P, Rosales R, Bruguera C, Yip P, Adeyi O, Selzner M, Selzner N. Assessment of Clinical Perfusates for Normothermic Ex-Vivo Liver Perfusion in a Porcine Model of Donation after Circulatory Death and Transplantation. American Journal of Transplantation. 2018 Jan;18 Suppl 2:13-99. doi: 10.1111/ajt.14572. Page 73. 2018
- Publicación. Sonya A. MacParland, Jeff C.Lui , Xue-Zhong, Brendan Innes, Agata Bartczak, Blair K. Gage, Justin Manuel, Nicholas Khuu, Juan Echeverri, Iván Linares, Rahul Gupta, 15 Michael Cheng, Lewis Y. Liu, Damra Camat, Sai W. Chung, Rebecca K. Seliga, Zigong Shao, Elizabeth Lee, Shinichiro Ogawa, Mina Ogawa, Michael Wilson, Jason E. Fish, Markus Selzner, Anand Ghanekar, David R. Grant, Paul D. Greig, Gonzalo Sapisochin, Nazia Selzner, Neil Winegarden, Oyedele A. Adeyi, Gordon Keller, Gary D. Bader, Ian D. MacGilvray. Dissecting the Human Liver Cellular Landscape By Single Cell RNA-Seq Reveals Novel Intrahepatic Monocyte/Macrophage Populations. Hepatology. 2018 October; 68 (S1). Page 17A. 2018
- Publicación. 7. Urbanellis P, Hamar M, Linares I, Kollmann D, Ganesh S, John R, Yip P, Mucsi I, Ghanekar A, Bagli D, Konvalinka A, Grant D, Robinson L, Selzner M. Normothermic Exvivo Kidney Perfusion Improves Function of Marginal Renal Grafts that were Subjected to Prolonged Ischemia Prior to Preservation. Transplantation. July 2018 - Volume 102 - Issue - p S377. doi: 10.1097/01.tp.0000543131.49738.80. 2018
- Publicación. Urbanellis P, Hamar M, Moritz K, Linares I, Kollmann D, Ganesh S, John R, Yip P, Mucsi I, Ghanekar A, Bagli D, Konvalinka A, Grant D, Robinson L, Selzner M. Normothermic Ex-Vivo Kidney Perfusion Restores the Genetic Profile of Marginal Kidney Grafts Subjected to Warm Ischemia. Transplantation. July 2018 - Volume 102 - Issue - p S397. doi: 10.1097/01.tp.0000543169.25082.af. 2018
- Hamar M, Urbanellis P, Kollmann D, Linares I, Ganesh S, Rosales R, Mucsi I, Konvalinka A, Bagli D, Ghanekar A, Kaths M, Yip P, John R, Robinson L, Selzner M. Comparison of Continuous Normothermic Ex Vivo Kidney Perfusion to Dynamic and Static Hypothermic Preservation Techniques in Porcine Kidneys Donated after Cardiac Death. Transplantation. July 2018 - Volume 102 - Issue - p S236. doi: 10.1097/01.tp.0000542910.28600.30. 2018
- Kollmann D, Linares I, Ganesh S, Rosales R, Hamar Matyas, Urbanellis P, Wiebe A, Yip P, Adeyi O, Selzner M, Selzner N. Platelet Aggregation Contributing to Reperfusion Injury can be Prevented by Normothermic Ex Vivo Liver Perfusion Prior to Liver Transplantation. Journal of Hepatology. 2018 April; 68: S69. PS-122. https://doi.org/10.1016/S0168-8278(18)30358-1. 2018
- Hamar M, Urbanellis P, Kollmann D, Linares I, Kaths M, Bagli D, Konvalinka A, Mucsi I, Ghanekar A, Robinson L, Selzner M. Comparison of Continuous NormothermIC Ex Vivo Kidney Perfusion to Hypothermic Preservation Methods in Pig Kidneys Donated after Cardiac Death. American Journal of Transplantation. 2018 May 4;18 Suppl 4:p160. doi: 10.1111/ajt.14916. 2018
- Publicación. Kollmann D, Linares I, Ganesh S, Rosales R, Tessandier N, Boilard E, Hamar M, Urbanellis P, Yip P, Adeyi O, Selzner M, Selzner N. Normothermic Ex Vivo Liver Perfusion Prior to Liver Transplantation Can Prevent Platelet Aggregation and Platelet Induced Sinusoidal Cell Injury. American Journal of Transplantation. 2018 May 4;18 Suppl 4:p224. doi: 10.1111/ajt.14916. 2018
- Publicación. Kollmann D, Linares I, Ganesh S, Rosales R, Tessandier N, Boilard E, Hamar M, Urbanellis P, Wiebe A, Yip P, Adeyi O, Selzner M, Selzner N. Normothermic Ex Vivo Liver Perfusion Prevents Platelet Sequestration and Platelet Induced Sinusoidal Cell Injury in the Liver When Compared to Static Cold Storage. Transplantation. 2018 May. Volume 102- Issue 5S- Supplement 1. O-050. doi: 10.1097/01.tp.0000534078.18014.88. 2018
- Publicación. Bartczak A, Linares I, Kollmann D, Zhang X-H, Ma X-Z, Echeverri J, Ganesh S, Manuel J, Selzner M, Keating A and McGilvray I. Towards the repair of marginal liver grafts: Mesenchymal stromal cell therapy. J Immunol. May 1, 2018, 200 (1 Supplement) 55.6. 2018
- Orador. In Vitro and In Vivo Administration of PPAR-y Agonist Reduces M1-Nitric Oxide+ Macrophage Phenotype and Ameliorates Hepatic Ischemia Reperfusion Injury. 2018 AASLD Liver Meeting. San Francisco. 2018
- Oraldor. Evaluation of Liver Viability During Porcine Normothermic Ex-Situ Perfusion in a Model of Liver Transplantation with Marginal Grafts. 2018 Sheila Sherlock Liver Research Day. Toronto. 2018
- Orador. In vivo and In vitro PPAR-y Activation Decreases M1-Macrophage Polarization and Improves Liver Ischemia Reperfusion Injury. 2018 International Liver Transplantation Society Conference. Portugal. 2018
- Autor. Póster: In vivo and In vitro PPAR-y Activation Decreases M1-Macrophage Polarization and Improves Liver Ischemia Reperfusion Injury. 2018 American Transplant Congress. Washington. 2018
- Autor. Póster: Assessment of Clinical Perfusates for Normothermic Ex-Vivo Liver Perfusion in a Porcine Model of Donation after Circulatory Death and Transplantation. 2018 ASTS. 18th Annual State of Art Winter Symposium. Miami. 2018
- Orador. Evaluación de Soluciones para Perfusión Hepática Ex-Vivo Normothermica en un Modelo de Trasplante de Hígado Posterior a Donación después de Muerte Circulatoria. 2017 V Americas Hepato-Pancreato-Biliary Association Congress/Mexican Chapter. Quintana Roo. 2017
- Supervisor. Conferencia de Liderazgo, Taller de Técnicas de Sutura. Health Occupations Students of America-HOSA Canadá. Toronto. 2017
- Publicación. Kaths JM, Cen JY, Chun YM, Echeverri J, Linares I, Ganesh S, Yip P, John R, Bagli D, Mucsi I, Ghanekar A, Grant D, Robinson LA, Selzner M. Continuous Normothermic Ex Vivo Kidney Perfusion is Superior to Brief Normothermic Perfusion Following Static Cold Storage in Donation After Circulatory Death Pig Kidney Transplantation. American Journal of Transplantation.2017 Apr;17(4)957-969. Doi: 10.1111/ajt.14059. Epub 2016 Oct 27. 2016
- Publicación. Linares I, Kollmann D, Echeverri J, Kaths M, Ganesh S, Hamar M, Urbanellis P, Rosales R, Bruguera C, Yip P, Adeyi O, Selzner M, Selzner N. Evaluation of Clinical Perfusates 12 for Normothermic Ex-Vivo Liver Perfusion in a Porcine Donor after Circulatory Death Model. Hepatology. 2017 October; 66 (S1). Page 75A. 2017
- Publicación. Linares I, Goldaracena N, Rosales R, De la Maza L, Kollmann D, Kaths M, Echeverri J, McCluskey S, Selzner N, Sapisochin G, Lilly L, Greig P, Bhat M, Ghanekar A, Cattral M, McGilvray I, Grant D, Selzner M. The New Event of Portal Vein Thrombosis Following Adult-to-Adult Living Donor Transplantation does not Affect Long Term Outcomes. Hepatology. 2017 October; 66 (S1). Page 890A. 2017
- Publicación. Linares I, Echeverri J, Kaths M, Ganesh S, Farroki K, Kollmann D, Adeyi O, Yip P, Hamar M, Urbanellis P, Selzner N, Selzner M. Targeting Kupffer Cell Polarization as Strategy to Ameliorate Liver Ischemia-Reperfusion Injury. Hepatology. 2017 October; 66 (S1). Page 383A. 2017
- Publicación. Linares I, Kollmann D, Echeverri J, Kaths M, Ganesh S, Hamar M, Urbanellis P, Rosales R, Bruguera C, Yip P, Adeyi O, Selzner N, Selzner M. Impact of STEEN vs Gelofusine as Perfusate during Normothermic Ex Vivo liver Perfusion on Outcome of Pig Liver Transplantation. Transplantation. 2017 May; Volume 101 - Issue 5S2 - p 1-416. doi: 10.1097/01.tp.0000520180.40625.72. 2017
- Publicación. Linares I, Goldaracena N, Rosales R, De la Maza L, Kollmann D, Kaths M, Echeverri J, McCluskey S, Selzner N, Sapisochin G, Lilly L, Greig P, Bhat M, Ghanekar A, Cattral M, McGilvray I, Grant D, Selzner M. De-Novo Portal Vein Thrombosis After Adult-toAdult Living Donor Liver Transplantation (LDLT) Does Not Impact on Long-Term Outcome. Transplantation. 2017 May; Volume 101 - Issue 5S2 - p 1-416. doi: 10.1097/01.tp.0000520180.40625.72. 2017
- Publicación. Linares I, Echeverri J, Kaths M, Ganesh S, Farroki K, Kollmann D, Adeyi O, Yip P, Hamar M, Urbanellis P, Selzner N, Selzner M. PPAR-γ Agonist Attenuates Hepatic IschemiaReperfusion Injury in a Mouse Model by Regulating Kupffer Cell Polarization. Transplantation. 2017 May; Volume 101 - Issue 5S2 - p 1-416. doi: 10.1097/01.tp.0000520180.40625.72. 2017
- Publicación. Linares I, Goldaracena N, Rosales R, De la Maza L, Kollmann D, Kaths M, Echeverri J, McCluskey S, Selzner N, Sapisochin G, Lilly L, Greig P, Bhat M, Ghanekar A, Cattral M, McGilvray I, Grant D, Selzner M. New Portal Vein Thrombosis After Adult-to-Adult Living Donor Liver Transplantation (LDLT) Does Not Impact on the Long-Term Outcomes. American Journal of Transplantation. 2017 January; 17(S2):74. https://doi.org/10.1111/ajt.14155. 2017
- Publicación. Urbanellis P, Hamar M, Linares I, Kollmann D, Cassol C, John R, Yip P, Mucsi I, Ghanekar A, Bagli D, Grant D, Robinson L, Selzner M. Normothermic Ex-Vivo Kidney Perfusion Improves Function of Extreme Marginal Renal Grafts Subjected to Prolonged Ischemia. American Journal of Transplantation. 2017 April; 17 (S3). 2017
- Orador. Evaluación de Soluciones para Perfusión Hepática Ex-Vivo Normothermica en un Modelo de Trasplante de Hígado Posterior a Donación Después de Muerte Circulatoria. 2017 V Americas Hepato-Pancreato-Biliary Association Congress/Mexican Chapter. Quintana Roo. 2017
- Autor. Póster: Evaluation of Clinical Perfusates for Normothermic Ex-Vivo Liver Perfusion in a Porcine Donor After Circulatory Death Model. 2017 CNTRP 4th Annual Scientific Meeting. Canadá. 2017
- Orador. Evaluation of Clinical Perfusates for Normothermic Ex-Vivo Liver Perfusion in a Porcine Donor After Circulatory Death Model. 2017 AASLD Liver Meeting. Washington. 2017
- Autor. Póster: The New Event of Portal Vein Thrombosis Following Adult-to-Adult Living Donor Transplantation does not Affect Long Term Outcomes. 2017 AASLD Liver Meeting. Washington. 2017
- Autor. Póster: Targeting Kupffer Cell Polarization as Strategy to Ameliorate Liver Ischemia Reperfusion Injury. 2017 AASLD Liver Meeting. Washington. 2017
- Orador. Targeting Kupffer Cells as a Strategy to Ameliorate Ischemia Reperfusion Injury in a Mouse Model. 2017 Canadian Society of Transplantation. Canadá. 2017
- Orador. Evaluation of Clinical Perfusates for Normothermic Ex-Vivo Liver Perfusion in a Donation After Circulatory Death Model. 2017 Canadian Society of Transplantation. Canadá. 2017
- Orador. De-novo Portal Vein Thrombosis after Adult-to-Adult Living Donor Liver Transplantation (LDLT) Does Not Impact on Long-term Outcome. 2017 Joint International Congress of ILTS, ELITA & LICAGE. 2017
- Orador. Impact of STEEN vs Gelofusine as Perfusate During Normothermic ex vivo Liver Perfusion on Outcome of Pig Liver Transplantation. 2017 Joint International Congress of ILTS, ELITA & LICAGE. 2017
- Autor. Póster: De-Novo Portal Vein Thrombosis After Adult-to-Adult Living Donor Liver Transplantation (LDLT) Does Not Impact on Long-Term Outcome. 2017 American Transplant Congress. Chicago. 2017
- Orador. PPAR-γ Agonist Attenuates Hepatic Ischemia-Reperfusion Injury in a Mice Model by Inducing M2 Kupffer Cell Polarization. 17th Annual State of Art Winter Symposium. American Society of Transplant Surgeons. Miami. 2017
- Autor. Póster: New Portal Vein Thrombosis After Adult-to-Adult Living Donor Liver Transplantation (LDLT) does not Impact on Long-Term Outcome. 17th Annual State of the Art Winter Symposium. American Society of Transplant Surgeons. Miami. 2017
- Orador. El Evento de Trombosis Venosa Portal de Novo Posterior a Trasplante Hepático de Donador Vivo no Afecta los Resultados a Corto y Largo Plazo. IV Americas Hepato-Pancreato-Biliary Association Congress, Mexican Chapter. Quintana Roo. 2016
- Supervisor. Conferencia de Liderazgo-Taller de Técnicas de Sutura. Health Occupations Students of America-HOSA Canada). Toronto. 2016
- Asistencia. Curso de donador de Órganos (Riñón, Hígado y Páncreas). Sociedad Canadiense de Trasplantes. Canadá. 2016
- Publicación. Bartczak A, Ma X-Z, Manuel J, Zhang X-H, Echeverri J, Linares I, Selzner M, Keating A and McGilvray I. Towards the Repair of Marginal Liver Grafts: Ex Vivo Mesenchymal Stromal Cell Perfusion. J Immunol. May 1, 2016, 196 (1 Supplement) 140.16. 2016
- Autor. Póster: Agonista del Receptor PPAR-γ Disminuye el Daño Hepático por Isquemiareperfusión (IR) al Inducir Polarización hacia Células de Kupffer del Tipo M2 en un Modelo Eurino. IV Americas Hepato-Pancreato-Biliary Association Congress, Mexican Chapter. Quintana Roo. 2016
- Autor. Póster: Comparación de los Vasodilatadores BQ123, Epoprostenol y Verapamilo durante Perfusión Hepática Normotérmica Ex-Vivo. ¿Cuál es la Mejor Opción? IV Americas Hepato-Pancreato-Biliary Association Congress, Mexican Chapter. Quintana Roo. 2016
- Orador. PPAR-γ Agonist As a Protective Strategy to Ameliorate Liver IschemiaReperfusion Injury in a Murine Model. 2016 Canadian Society of Transplantation. Annual Scientific Meeting. Canadá. 2016
- Autor. Póster: Portal Vein Thrombosis After Adult-to-Adult Living Donor Liver Transplantation (LDLT) and Its Short and Long-term Outcomes. 2016 Canadian Society of Transplantation, Annual Scientific Meeting. Canadá. 2016
- Asistencia. Curso de Microcirugía. Centro Médico Nacional Siglo XXI, IMSS. Ciudad de México. 2014
- Asistencia. Curso de Cirugía Laparoscópica. Asociación Mexicana de Cirugía. Ciudad de México. 2013
- Autor. Póster: Sporadic Visceral Neuropathy. Rare Cause of Megacolon. 37th International Congress of General Surgery. Guerrero. 2013
- Coordinador. Curso de Preparación para el ENARM. Universidad Autónoma de San Luis Potosí (UASLP). San Luis Potosí. 2010
- Asistencia. Curso: Soporte Cardiovascular Avanzado. American Heart Association. San Luis Potosí. 2010
- Asistencia. Curso: Soporte Cardiovascular Avanzado Pediátrico. American Heart Association. San Luis Potosí. 2009
- Autor. Póster: Falla Orgánica Múltiple Secundaria a Infección Micótica Sistémica en Pacientes con Lupus Eritematoso Generalizado. XXXV Congreso Mexicano de Reumatología. Chihuahua. 2007
- Asistencia. Curso: Estimulación Cognitiva Posterior a Daño Cerebral. Universidad Complutense de Madrid. España. 2006
- Orador. Carcinoma Tubulo-Lobular de Mama, Variante Lobular. Michoacán. 2004
Premios y reconocimientos
- Ganador. Top Poster of Distinction Award at 2019 American Transplant Congress. Normothermic Ex Situ Perfusion with Different Clinical Perfusates and Their Effect on Pig Liver Transplant Outcomes in a Donation after Circulatory Death Model. 2019
- Ganador. Young Investigator Award. 2019 International Liver Transplantation Society, Annual International Congress. Liver Viability Parameters During Normothermic Ex-situ Liver Perfusion in a Porcine Model of Liver Transplantation with Marginal Grafts. Canadá. 2019
- Ganador. University Health Network Transplant Fellowship Competition Award. Toronto. 2019
- Ganador. Top Poster of Distinction Award at 2018 American Transplant Congress for: Normothermic Ex-Vivo Kidney Perfusion Restores the Genetic Profile of Marginal Grafts Subjected to Warm Ischemia. 2018
- Ganador. Top Poster of Distinction Award at 18th Annual State of the Art Winter Symposium for: Metabolic Assessment of Graft Function During Ex Vivo Liver Perfusion Prior to Transplantation. 2018
- Ganador. Best Oral Presentation at 2017 Sheila Sherlock Liver Research Day. Toronto. 2017
- Ganador. Top Poster of Distinction Award at 2017 American Transplant Congress for: Normothermic Ex-Vivo Kidney Perfusion Improves Function of Extreme Marginal Renal Grafts Subjected to Prolonged Ischemia. 2017
- Ganador. Top Poster of Distinction award at 2017 American Transplant Congress for: De-novo Portal Vein Thrombosis After Adult-to-Adult Living Donor Liver Transplantation (LDLT) does not Impact on Short and Long-Term Outcome. 2017
- Ganador. Top Poster of Distinction Award at 2017 American Transplant Congress for: Impact of STEEN vs Gelofusine as Perfusate during Normothermic Ex Vivo Liver Perfusion on Outcome of Pig Liver Transplantation. 2017
- Ganador. Top Abstracts for Oral Presentation. 17th Annual State of the Art Winter Symposium. American Society of Transplant Surgeons. 2017
- Ganador. Top Poster of Distinction Award at Americas Hepato-Pancreato-Biliary Association Congress, Mexican Chapter (IV). 2016
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